Summer-Newsletter-2026.-v6 - Flipbook - Page 11
Summer 2026
Review of the peripheral blood smear on the DI-60™ Automated
Ditgital Cell Morphology Analyzer shows typical-looking neutrophils
with no overt dysplasia, small round lymphocytes (some with scant
cytoplasm) and reactive-appearing monocytes. Red cell morphology is
remarkable for the presence of target cells and schistocytes. The WBC
count obtained from the WDF channel can be veri昀椀ed. In addition, the
XN detected a small population of WBCs with high 昀氀uorescence and
moderate complexity (circled in red on the WDF scattergram). This
population may represent the large, reactive monocytes shown below.
Although RBC fragments are present in the sample, this is not likely the
source of the interference in the WNR scattergram. The lysing reagent
used in the WNR channel is harsher than the reagent used in the WDF
channel and can possibly cause WBC fragmentation; this may be why
there is debris interference in the WNR channel but not in the WDF
channel. The source of the fragile cells in this sample is likely due to
chemotherapy treatment or circulating tumor cells.
Potential next steps for this specimen may include:
• Retest with WNR & WDF modes (CBC + DIFF), if not
already ordered
• Perform WBC estimate by peripheral smear review
• Consult with lab pathologist to review clinical history, treatment,
results and additional result comments (if needed)
Fall 2026
Webinar
Series
Coming soon!
Why not kick off this back-toschool season and earn new
continuing education contact hours
by attending Sysmex's newest
live webinars?
Mark Your Calendar
• September 23
• October 21
• November 18
• December 16
Stay tuned to hear from our best-inclass speakers on industry-leading
topics, such as advanced CBC
parameters, hemostasis testing and
more!
Neutrophils
Lymphocytes
Monocytes
Check our website
here to see information
on the upcoming
webinar series.
RBC Morphology
NEWS |
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